Medical Bacteriology

Medical Bacteriology:

Medical Bacteriology is the study of bacteria which is responsible for human disease. The field covers the detection and recognition of bacterial pathogens, determination of the sensitivity and methods of resistance of bacteria to antibiotics, the methods of virulence, and few aspects of immunity to the infection.

The clinical bacteriology recognizes bacterial pathogens exist in specimens like sputum, blood, pus, and spinal fluid, or from swabs of skin, throat, or rectal surfaces. Recognition includes direct staining and microscopic examination of such materials and isolation of bacteria existed in the material by growth in suitable media. The laboratory should distinguish bacterial pathogens from undisruptive bacteria which colonize humans. Species and virulent strains of bacteria can be recognized on the basis of expansion properties, metabolic and biochemical tests, and reactivity with particular antibodies.

Latest advances in the field of diagnostic bacteriology have comprised automation of biochemical testing; the development of quick antibody-based detection techniques; and the application of molecular biology methods. Once a bacterial pathogen has been recognized, a main responsibility of the diagnostic bacteriology laboratory is the identification of the sensitivity of the pathogen to antibiotics. It includes observation of the growth of the bacteria in the existence of different concentrations of antibiotics. The procedure has been made more proficient by the development of automatic instrumentation.

The existence of particular antibodies is often helpful in the diagnosis of bacterial diseases in which the pathogen is or else hard to detect.

 

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