Antimicrobial Resistance

Antimicrobial Resistance:

Pathogenic microbes are given with their own methods to establish infection in the host animals and humans. Likewise the host’s body has a number of defense mechanisms to increase resistance against the invasion and to prevent infection of pathogens. The antimicrobial response of hosts might be natural, non-specific and particular. Natural resistance comprises species resistance, racial resistance and individual resistance

Key facts:

  • Infections caused by resistant microorganisms frequently fail to respond to conventional treatment, resultant in prolonged illness and bigger risk of death.
  • Around 440 000 new cases of multidrug-resistant tuberculosis (i.e.,MDR-TB) emerge annually, causing at least 150000 deaths.
  • Resistance to prior generation antimalarial medicines like chloroquine and sulfadoxine-pyrimethamine is widespread in most of the malaria-endemic countries.
  • A big percentage of hospital-acquired infections are caused by highly resistant bacteria like methicillin-resistant Staphylococcus aureus (i.e., MRSA).
  • Unsuitable and irrational utilize of antimicrobial medicines gives favourable conditions for resistant microorganisms to emerge, spread and persist.

 

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