Treatment of enteric fever:
Chloramphenicol is efficient in fast clinical enhancement and a dramatic refuse in mortality. However it was noted that faecal excretion of organisms continued throughout treatment and that the incidence of relapses was raised. Co-trimoxazole (i.e., trimethoprimsulpha- methoxazole) can be a helpful second-line drug. The fluoro-quinolones are active by mouth, penetrate fine in tissues and are concentrated in phagocytes and bile and have been extremely efficient in treating enteric fever. Ciprofloxacin and ofloxacin has been most generally employed and found superior to ceftriaxone. They symbolize the drugs of selection in the treatment of enteric fever.
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