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  Prevention of establishment of organism

Prevention of establishment of organism in susceptible host:

Once it is acknowledged that the host had a contact with infected individual or convalescent carrier chemoprophylaxis should be offered to prevent the establishment of the organisms in the tissues.

Prevention of toxin acting on target cells:

When it is known that the organism is established in the tissues and toxin manufacture is expected, the destructive effect of toxin is neutralized by Antitoxin treatment. Antitoxin is generated in animals [i.e., Horses, Rabbits, goat & sheep]. A dose of 20,000 or 1 lakh units are injected intra-muscularly or intra-venously. Hypersensitivity toward animal proteins is check by skin or conjunctival test. Moreover, production of toxin is prevented by treating the patients with antibiotics like penicillin or erythromycin.

Prevention of establishment of carrier state:

Patients should be treated with antibiotics and hence they do not become carriers of the organisms.

 

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