Morphology:
L.donovani multiplies within reticulo endothelial system. It splits by binary fission and the cells are packed with 50-200 amastigotes –termed as Leishman-Donavan (i.e., LD) bodies. They are released by the lysis of the cells and the parasites attack fresh cells. Blood sucking insects take free leishmania and phagocytosed ones. In sand flies amastigotes converted into promastigotes. They multiply by binary fission in the mid gut and spread forward and reach buccal cavity in 6 to 9 days. This is termed as anterior station development. Such are introduced into new host by the bite of P. argentipus.
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