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  Immunology

Immunology:

Immunology is a biomedical science branch that deals with the response of an organism to antigenic challenge and its acknowledgment of what is self and what is not. This deals with the defense mechanisms involving all physical, chemical and biological properties of the organism that aid it to combat its susceptibility to foreign organisms, material, and so on.

Immunology deals with physiological operation of the immune system in states of both health and disease and also malfunctions of the immune system in immunological disorders such as allergies, immune deficiency, hypersensitivities, transplant rejection and autoimmune disorders.

Immunology deals with chemical, physical, and physiological characteristics of the components of the immune system in vitro, in situ, and in vivo. Immunology has a huge array of utilizations in numerous disciplines of science and medical science.

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Innate and adaptive immune systems:

The immune system is categorized into those that are static, or innate to the organism, and those that are responsive, or adaptive to a potential pathogen or foreign substance.

The innate system of immunity is on evolutionary terms, the older system which forms the primary line of defense. This is non-specific and the resistance is static (it does not enhance with repeated exposure and there is no memory on subsequent exposures). It involves physical defenses like skin & epithelial surfaces and so on. Others are biochemical defenses like soluble-lysosyme, acute phase reactants and complement, fibronectin, interferons. Cellular components involve natural killer cells, RES phagocytes.

The adaptive system is the second line of defense and is activated just once the innate system has been overwhelmed. It is particular to the infective agent and can store the information concerning the invader as memory to exhibit an enhanced response to following challenge.

 

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