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  Metabolism of Proteins

Metabolism of Proteins:

The ingested proteins that are metabolised to amino acids via peptide bond cleaving enzymes termed as proteinases.

General reactions of amino acids:

The general reactions of amino acids involve transamination, deamination, and decarboxylation. The reactions of deamination and transamination carry about the creation of keto acids that can go through a further series of changes. Inter-conversion among amino acids and keto acids results in the synthesis of several nutritionally non necessary amino acids. These give for the synthesis of protein and necessary non-protein nitrogenous materials. Throughout the protein synthesis the amino acids are absorbed from the blood, like the liver does not store them.

Catabolism of amino acids

Even though each amino acid follows its own particular metabolic pathway, some general reactions are found to be general in the catabolism of almost all the amino acids. Several of the amino acids are transformed to α-keto acids by the removal of nitrogen in the type of ammonia that is rapidly converted into urea or it gets incorporated into a number of other amino acids.

1. Oxidative deamination
2. Transamination
3. Decarboxylation
4. Transmethylation
5. Catabolism of the carbon skeleton of amino acids

 

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