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  Clinical Manifestations

Clinical Manifestations:

Cutaneous and Mucosal Candidiasis:

The superficial candidiasis is viewed in normal persons. AIDS, diabetes, pregnancy, young and old age, birth control pills and trauma are the risk factors related with candidiasis.

Oral thrush takes place on the lips, tongue, gums or palate. It is a white patch with epithelial cells, yeast and pseudo hyphae. Oral thrush generates in most of the AIDS patients.

Candida attacks the mucosa of the vagina and causes vulvo vaginitis that is characterized by pruritis, irritation, and vaginal discharge.  This modifies the microbial flora, local acidity or secretions.

Candida attacks the skin and causes infection in the moist, warm portions of the body like the axillae, groin and intergluteal folds. The infected region becomes red and moist and might develop deep vesicles. Interdigital participation is most general in home makers, cooks, vegetable and fish handlers. It too causes infection of the nails and around the nail plates and is termed as onychomycosis, a painful, erythematous swelling of the nail fold.

Systemic Candidiasis:

In normal persons when candidemia takes place, normal host defenses remove candida. However candida invades blood stream in persons after surgery, intravenous drug abuse and in indwelling catheter patients. Systemic candidiasis is related with chronic administration of corticosteroids or other immunosuppressive drugs. Candida causes endocarditis and as well kidney infections, while urinary tract infections are frequently related with catheters, diabetes, pregnancy and antibacterial antibiotics. In cellular immuno-deficiency persons, candida causes chronic mucocutaneous infection from early on childhood. There is no particular site for candida infection in the body.

 

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