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  Processing of mRNA molecules

Processing of mRNA molecules:

MRNA (messenger RNA) goes through various modifications before it is being translated. They are

1. Addition of blocks of poly A, consisting of 200 (or) more AMP residues to the 3' end of messenger RNAs. This addition of poly A tail occurs in the nucleus.

2. A methylated Guanine nucleotide known as “5' cap” is added to the 5' end of mRNA molecule.

3. Methylation takes place in the internal adenylate nucleotides at their N-6 position. The function of it is not known.
Thus mRNA (messenger RNA) is processed to obtain the active mRNA molecule.

1142_mrna molecules.jpg

                                                                   Structure of Active mRNA

 

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