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  Biological Database

Biological Database:

Definition of Database:

‘Creating’ database means a coherent gathering of data with inherent meaning, employed for future application. Database is a common repository of voluminous information or records to be procedure by a program.

Databases are generally classified as specialized databases and generalized databases. Structural organization of DNA, carbohydrates, protein, is involved under generalized databases. Databases of Expressed Sequence Tags (i.e., ESTs), Genome Survey Sequences (i.e., GSS), Single Nucleotide Polymorphisms (i.e., SNPs) and sequence Tagged sites (i.e., STSs). RNA databases are involved under specialized data bases.

Generalized databases have sequence database and structure databases.

a. Sequence databases are the series records of either nucleotide or amino acids. The previous is the nucleic acid databases and the later are protein sequence databases.

b. Structure databases are individual records of macromolecular structures. The nucleic acid databases are once more categorized into primary databases and secondary databases.

Primary databases have data in their original form taken as such from the source example, SWISS-PROT (Switzerland), Genebank (NCBI/USA) Protein, Protein 3D structure and so on.

Secondary databases also termed as value added databases have annotated data and information example, GDB - Genome Database – Human, OMIN – Online Mendelian Inheritance in Man.

 

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