Pathogenesis:
The typical course of HIV infection’s duration is around ten years. There are different phases of HIV infection involving primary infection, dissemination of virus to lymphoid organs, induction of HIV expression, clinical latency, clinical disease & death. The duration between main infection and progression to clinical disease averages around10 years. Death generally takes place within 2 to 5 years after the onset of clinical symptoms.Clinical manifestations:
According to the Center for Disease Control, (i.e., in USA) the HIV infection and its squeal are categorized into four classes:
Group I – Acute HIV infection or seroconversion illnessGroup II – Clinical latency or asymptomaticGroup III – Persistent generalized lymphadenopathyGroup IV – A – Constitutional disease
B – Neurologic diseaseC – Secondary infectious diseaseD – Secondary cancersE – Other conditions
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