Invasive soft tissue infection

Invasive soft tissue infection:

Sometimes Str. pyogenes enters internal body structures and establishes harsh invasive infections. Necrotizing fasciitis, streptococcal toxic shock syndrome and puerperal fever are a few infections related with bacteraemia.

A. Necrotizing fasciitis:

In this infection, quick destruction of fat and fascia takes place. Str. pyogenes enters such tissues via skin after minor trauma. However skin might show minimal signs of infection. Systemic shock and common deterioration take place very rapid. It affects both immunocompetent and immune-suppressed individuals. Streptococci can be isolated from the blood, blister fluid and culture of infected regions.

B. Streptococcal toxic shock syndrome:

Streptococcal toxic shock syndrome is an acute fulminating disease that might develop in patients with necrotizing fasciitis, or with invasive becteraemic streptococcal infections. The disease takes place due to the discharge of toxins in the blood. The clinical signs resemble staphylococcal TSS. Fever, nausea, malaise, vomiting, and diarrhea, dizziness, confusion and a flat rash over large portions of the body might also be existed.

C. Puerperal sepsis:

When the streptococci enter the uterus after delivery, puerperal fever develops. Streptococci from endometrium enter the blood and cause septicemia. Subsequent to the introduction of antibiotic therapy this situation takes place rarely.


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