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  Actinomycotic Granules

Actinomycotic Granules:

A) Yellow or white or pink granules are generated by them. For isolation SDA medium with or without antibiotics is employed. The

B) plates are incubated at room temperature and 37°C.

C) Biochemical test are utilized mainly for Nocardia and Streptomyces species.

D) Animal pathogenicity is completed for Nocardia species for which swiss mice are employed.

Cultures:

Samples must also be cultured at 25 to 30°C and 37°C, on Brain heart infusion agar or blood agar for Actinomycetes and on Sabouraud’s agar for Eumycotic agents. The fungi which cause eumycetoma are all septate moulds. They emerge in culture within 1-4 weeks. Serological precipitin tests are employed to distinguish between eumycetoma and actionomycetoma and also to recognize the specific organisms. However they are of little value for diagnosis in routine usage.

Treatment:

Eumycetoma does not respond to chemotherapy and radical surgery is generally essential. For cutaneous form treatment with potassium iodide is satisfactory. In disseminated disease intravenous amphotericin B is needed.

Epidemiology and Control:

Organisms generating mycetoma take place in soil and on vegetation. Barefoot farm laborers are mainly exposed. Proper cleaning of wounds and wearing shoes are logical control measures.

 

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