Problem: Ms. H, a 37-year-old woman, present with radiating sciatic pain that worsens during menstruation. MRI reveals endometriotic nodules along the sciatic nerve pathway. Which of the following best describes the mechanism of nerve-related pain and endometriosis? Need Assignment Help? Progesterone-induced demyelination of pelvic nerves causes cyclic neuropathy. Endometriotic implants invade nerve fibers, triggering local inflammation. And neuropathic pain. Estrogen-dependent vasodilation increases nerve sensitivity, leading to pain perception. Retrograde menstrual blood flow accumulates around peripheral nerves, compressing them.