Explain how cancer cells take advantage of checkpoint


Problem

1) What is cancer Immunotherapy?

2) What are checkpoint inhibitors?

3) Describe two check point inhibitors (How they function, what they are made of, and what do they check)

"The immune system has checkpoint proteins (such as PD-1 and CTLA-4) that help keep it from attacking other normal cells in the body. Cancer cells sometimes take advantage of these checkpoints to avoid being attacked by the immune system. Targeting these checkpoints is quickly becoming an important part of the treatment for some cancers, including melanoma and non-small cell lung cancer. Researchers have also found promising early results against a number of other cancer types. Unlike most other cancer drugs, these checkpoint inhibitors seem to be helpful against many different types of cancer."

1) Describe the immunology behind this quote.

2) Explain how cancer cells take advantage of checkpoint.

3) Why are cancer cells allowed to attack their own body cells?

4) How does targeting these check points help with cancer treatment?

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Biology: Explain how cancer cells take advantage of checkpoint
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