Clinical Manifestation of Herpes Viruses:Oropharyngeal diseases:
Primary HSV -1 infection are generally asymptomatic. Symptomatic infection is general in children (1 to 5 years) and comprises the buccal and gingival mucosa of the mouth. Symptoms comprise sore throat, fever, vesicular and ulcerative lesions, edema, gingivostomatitis and gingivitis.
In adults, HSV1 causes tonsillitis and pharyngitis. Recurrent disease is characterized by a cluster of vesicles most generally localized at the border of the lips.
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