Reactions of glycolytic pathway:
Chain of reactions of glycolytic pathway that degrades glucose to pyruvate is presented below. The sequence of reactions taking place in glycolysis may be referred below four stages.
Stage I:
Stage I is a preparatory phase. Earlier than the glucose molecule can be break down, the rather asymmetric glucose molecule is transformed to approximately symmetrical form, fructose 1,6-diphosphate through donation of 2 phosphate groups from ATP.
Diagram: The glycolytic pathway(A) Uptake of glucose by cells and its phosphorylation:
Glucose is independently permeable to intestinal mucosa, liver cells, and kidney tubules in which glucose is taken up through the 'active' transport. In another tissue insulin makes easy the uptake of glucose. Glucose is phosphorylated to create glucose 6-phosphate. The enzyme included within this reaction is glucokinase. This reaction is cannot be change.
(B) Conversion of glucose 6-phosphate to fructose 6-phosphate:
Glucose 6-phosphate is transformed to fructose 6-phosphate through the enzyme phosphogluco isomerase.
(C) Conversion of fructose 6-phosphate to fructose 1,6 diphosphate:
Fructose 6-phosphate is phosphorylated irretrievably at 1 position catalyzed via the enzyme phosphofructokinase to generate fructose 1, 6-diphosphate.
Stage II:
(A) Actual splitting of fructose 1, 6 diphosphate:
Fructose 1, 6 diphosphate is break down via the enzyme aldolase in two molecules of triose phosphates that are:
The reaction is reversible. There is neither expenditure of energy nor creation of ATP.
(B) Interconvertion of triose phosphates:
Both of the triose phosphates are interconvertible
Stage III:
Stage III is the energy yielding stage. Reactions of this kind where an aldehyde group is oxidised to an acid are accompanied through liberation of large amounts of potentially helpful energy.
(A) Oxidation of glyceraldehyde 3-phosphate to 1,3-bisphosphoglycerate Glycolysis carries on via the oxidation of glyceraldehydes 3-phosphate to create 1, 3 bisphosphoglycerate. The reaction is catalyzed via the enzyme glyceraldehyde 3-phosphate dehydrogenase
(B) Conversion of 1, 3-bisphosphoglycerate to 3-phosphoglycerate:The reaction is catalyzed via the enzyme phosphoglycerate kinase. The extreme energy phosphate bond at position - 1 is transferred to ADP (Adenosine Di-phosphate) to form ATP (Adenosine Tri-Phosphate) molecule.
Stage IV:
Stage IV is the recovery of the phosphate group from 3-phosphoglycerate. The 2 molecules of 3-phosphoglycerate, the end-product of the preceding stage, yet keeps the phosphate group, initially imitative from ATP (Adenosine Tri-Phosphate) in Stage I.
(A) Conversion of 3-phosphoglycerate to 2-phosphoglycerate:
3-phosphoglycerate created via the above reaction is converted to 2-phosphoglycerate, catalyzed via the enzyme phosphoglycerate mutase.
(B) Conversion of 2-phosphoglycerate to phosphoenol pyruvate:
The reaction is catalyzed via the enzyme enolase, the enzyme needs the existence of either Mg2+ or Mn2+ ions for activity.
(C) Conversion of phosphoenol pyruvate to pyruvate:
Phosphoenol pyruvate is transformed to pyruvate, the reaction is catalysed via the enzyme pyruvate kinase. The phosphoenol pyruvate’s high energy phosphate group is directly transferred to ADP (Adenosine Di-phosphate), producing ATP (Adenosine Tri-Phosphate). The reaction is cannot be reversible.
Latest technology based Biology Online Tutoring Assistance
Tutors, at the www.tutorsglobe.com, take pledge to provide full satisfaction and assurance in Reactions of glycolytic pathway homework help via online tutoring. Students are getting 100% satisfaction by online tutors across the globe. Here you can get homework help for Reactions of glycolytic pathway, project ideas and tutorials. We provide email based Reactions of glycolytic pathway homework help. You can join us to ask queries 24x7 with live, experienced and qualified online tutors specialized in Reactions of glycolytic pathway. Through Online Tutoring, you would be able to complete your homework or assignments at your home. Tutors at the TutorsGlobe are committed to provide the best quality online tutoring assistance for Biology homework help and assignment help services. They use their experience, as they have solved thousands of the Biology assignments, which may help you to solve your complex issues of Reactions of glycolytic pathway. TutorsGlobe assure for the best quality compliance to your homework. Compromise with quality is not in our dictionary. If we feel that we are not able to provide the homework help as per the deadline or given instruction by the student, we refund the money of the student without any delay.
We offer First-class Graph Theory Assignment Help service at most viable prices which always make you stand out from your peers.
build up the layout of a lap winding for a 3 phase ac machine comprising 4 pole and 24 slots. there are 2 coil sides per slot.
let 24x7 available professional tutors of sorting assignment help service help you in securing a++ at pocket-friendly prices.
logic gates process signals that present true or false. generally the positive supply voltage +vs present true and 0v represents false.
Fluorimetry tutorial all along with the key concepts of Mode of Operation of the Instrument, Quenching, Applications, Precautions for usage
Theory and lecture notes of Expected Future Changes in the Macroeconomy all along with the key concepts of expected future changes in the macroeconomy, History of Macroeconomic Fluctuations. Tutorsglobe offers homework help, assignment help and tutor’s assistance on Expected Future Changes in the Macroeconomy.
www.tutorsglobe.com offers linear algebra homework help, linear algebra assignment help, online tutoring assistance, math solutions by online qualified tutor's help.
tutorsglobe.com respiration assignment help-homework help by online human physiology tutors
Theory and lecture notes of Correlation & Regression all along with the key concepts of Coefficient of Determination, Correlation Coefficient, Dependent Variable, Independent Variable and Regression Line. Tutorsglobe offers homework help, assignment help and tutor’s assistance on Concept of Correlation & Regression.
tutorsglobe.com structure of a virus assignment help-homework help by online viruses tutors
There are two issues that can be taken to preparing the statement of cash flows: the direct method and the indirect method.
Volumetric Analysis tutorial all along with the key concepts of Principle, Requirements, Procedure, Observations and Results, Treatment of Results, Experiment 2B
Theory and lecture notes of Theory of Expected Utility all along with the key concepts of theory of expected utility, Petersburg Paradox, Nicholas Bernoulli. Tutorsglobe offers homework help, assignment help and tutor’s assistance on Theory of Expected Utility.
score impeccable grades and get appreciation from professors with data warehouse-data mining assignment help at feasible prices.
online mcat exam preparation course and online mcat tutoring package offered by tutorsglobe are the most comprehensive and customized collection of study resources on the web, offering best collection of mcat practice papers, quizzes, mcat test papers, and guidance.
1950970
Questions Asked
3689
Tutors
1469351
Questions Answered
Start Excelling in your courses, Ask an Expert and get answers for your homework and assignments!!