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  Formation of Melanin

Formation of Melanin:

The melanin’s, the skin’s pigments and hair are complex polymers where a major constituent is created from tyrosine through dihydroxy phenyl alanine (DOPA).

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The creation of melanin’s from tyrosine that takes place in animals, plants and specific bacteria (B. niger), is because of the action of polyphenol oxidases/tyrosinases. Tyrosinase, is a copper comprising mixed function oxidase which performs a tricky sequence.

When the melanin’s of persons are derived from tyrosine by DOPA, several polyhydroxy phenyl and aminophenyl compounds comprising ortho/para groups can be oxidized to pigmented polymers and the sort of melanin is best displayed through pointing out the substance from which the melanin is created. So we may comprise homogentisic acid-melanin, dopa-melanin, adrenaline-melanin, p-phenylenediamine melanin etc.

Melanin creates a reversible oxidation-reduction system, where the reduced type is tan and the oxidized type is black. Melanin’s come out in tissues as regular, spheroid granules and presented formed elements than precipitated aggregates. Melanin’s are generated in pigment-the melanocytes, forming cells, and their creation is stimulated through adrenal cortical and particularly pituitary hormones.

 

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