Question: You are studying patients who are struggling with constant joint pain, and you discover they all have one thing in common: they were infected with chikungunya virus! The odd part is, they've cleared this infection months ago, and you cannot isolate any infectious virions from any patients. Interestingly, you can still find some genomic fragments of the virus persisting in the cells of these patients. Why could this be problematic for the patient? Why could this lead to constant joint pain? (Hint: what kind of genome do alphaviruses have?)