Problem:
Recall Mr. M, the 51-year-old obese man, with a sedentary lifestyle (desk job) from Exam I. Though he consumed a mood altering agent for pain in Exam I, he recently had surgery for his knee and was prescribed a different pain medication during recovery (medication D). Unfortunately, his surgery did not alleviate his pain, and he continued using medication D longer term. Over time, with the same dose of medication D, his pain symptoms became worse and worse. In response, his care team would increase his medication D dosage, and then his pain would lessen, only to return again. This occurred through several rounds, until finally, Mr. M's providers prescribed a different medication (medication K), which worked well, even at low doses. 1. Where medication D acts in the CNS (suggest one specific location)