What is the reversal potential of the channel, Other Subject

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What is the reversal potential of the channel

Problem

You are studying an ionotropic receptor from a mutant species. The receptor binds to GABA and the channel is selective for Cl- and K+. The equilibrium potentials of these ions are -70 and -80 mV, respectively.

• What is the reversal potential of this channel?
• When GABA binds the receptor what will you see if the RMP is -65Mv?
• What will happen if you hold the membrane at -80Mv what ion will be responsible for what you observe?

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