Problem
Case Study: A 22-year-old man is brought to the emergency room unresponsive and in respiratory distress. He was found unconscious at home next to a suicide note and an empty bottle of methanol. A brief history from an accompanying family member is significant for the patient having depression, but he is not currently on any medications. On examination he is not responsive to verbal stimuli but has pupillary and pain responses, and he is tachypneic and tachycardic (rapid respiratory and heart rates). His lungs are clear. You quickly institute supportive measures, intubate the patient, and send blood tests that confirm a profound anion-gap metabolic acidosis. No other drugs are found in his system. You diagnose him with an acute methanol overdose, start him on IV fluids, sodium bicarbonate, and an IV infusion of ethanol.
• What are the uses of methanol?
• What is the enzymatic pathway for methanol metabolism?
This is a graduate-level pharmacology course. Please answer the question clearly and in-depth. I will need you to provide your CITATIONS as well or I will have to send back the answer. I recommend PubMed, NIH, and Science Direct.