What is first-line therapy for osteoarthritis and mechanism


Problem

a) What is the first-line therapy for osteoarthritis and the mechanism of action?

b) Sally expresses concern about all the recent news about heart problems and celecoxib (Celebrex). What information should be included in a teaching plan to help her understand about taking celecoxib and the benefits and risks?

c) Ibuprofen and celecoxib are both nonsteroidal anti-inflammatory drugs. Explain how they are similar and different.

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