Problem:
Congenital adrenal hyperplasia (CAH) is an autosomal recessive disease that results in developmental and physiological abnormalities, sometimes severe enough to cause death. About 1 in 12,500 children is born with this condition.
Required:
Question 1: Determine the allele frequencies for the normal and abnormal alleles.
Question 2: Determine the frequency of carriers in the population.
Show the pedigree and your calculation.