Question: Pick the two "difficulties and disasters" that are most likely to be a problem in the following study, and explain why each would be a problem: A researcher at a large medical clinic wants to determine whether a high-fat diet in childhood is more likely to result in heart disease in later life. As a case- control study, she gives a questionnaire about childhood diet to 500 patients with heart disease and 500 patients without heart disease matched by age and sex.