Problem:
Question 1: How might the loss of a tumor suppressor gene function yield an outcome that is(at the cell level) indistinguishable from the acquisition of an active oncogene?
Question 2: Mice that are homozygous for a complete deletion of the wild-type gene "T" develop multiple tumors in a variety of tissues very early in life. Gene "T" is most likely
A) an oncogene.
B) an activated oncogene.
C) a proto-oncogene.
D) a dominant tumor suppressor gene.
E) a tumor suppressor gene.
Give reasoning with your answer.