How many receptors have been found for opioids, Other Subject

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How many receptors have been found for opioids

Problem: Read the following scientific review article (Pathan H. & Williams J. Basic opioid pharmacology: an update. Br. J. Pain 6(1): 11-16 (2012) and do some research on NCBI PubMed and discuss the following aspects

Q1. How many receptors have been found for opioids? What are their names?

Q2. How do those opioid receptors differ? Which components do they share?

Q3. What is known about the intracellular signaling pathways of those opioid receptors?

Q4. In which way might increased knowledge about the intracellular signaling components of the opioid receptor help to develop new generations of analgesics without addictive properties?

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