Problem: Homeostasis refers to the tendency of the body to maintain a relatively constant internal environment even when external conditions vary greatly. For example, on a very cold or extremely hot day, the internal temperature of the body remains within a range of about 36° to 37°C. Why is homeostasis important for enzyme function? Include an explanation of how factors such as temperature and pH change the shape of enzyme molecules and decrease or destroy the ability of enzymes to bind their substrate molecules.