Below are 3 questions regarding the pharmacokinetic parameter. Read the instruction and follow the direction. Each question can be described in a paragraph or two.
Using Lexicomp , briefly compare the stated pharmacokinetic parameters of acetaminophen and ibuprofen in the following THREE questions:
a. In healthy adults, comparing acetaminophen and ibuprofen, which pharmacokinetic parameters are similar and which are significantly different ?
b. How does recommended dose and method for determining dose differ from adult dosing when considering healthy children between 6 months old and 15 years old?
c. patient with renal impairment who requires post-operative pain medication. According to Lexicomp, how should acetaminophen therapy be adjusted to account for this condition and which other easily adjustable parameter(s) might you consider modifying?