How baseline assessments were conducted with participants


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Can you make this more comprehensive: "Data Collection: Baseline assessments were conducted with the participants, during which various measures were collected. Substance use was assessed through interviews and urine drug screens, covering a range of substances such as tobacco, alcohol, cannabis, cocaine, methamphetamine, and opioids. The severity of psychosis was also assessed. Mortality data were collected from coroner's reports and hospital records. Here are the key data collection methods used in this study: The document provides details on the baseline assessment, psychiatric diagnosis, and mortality data collection methods used in the study: 1. Baseline Assessment: Sociodemographic variables were recorded by a research assistant. A psychiatrist performed a mental status examination, and a focused neurological exam was conducted. A Mini-International Neuropsychiatric Interview (MINI) was used to assess participants' mental health histories, and health care records were obtained to provide additional historical information. 2. Psychiatric Diagnosis: Baseline psychiatric symptoms were assessed using the 30-item Positive and Negative Syndrome Scale (PANSS) for functioning, along with the Social and Occupational Functioning Assessment Scale (SOFAS) and the Role Functioning Scale (RFS). Diagnoses of current and past mental and substance use disorders were made by study psychiatrists using all available information, according to criteria from the Diagnostic and Statistical Manual for Mental Disorders-TR Fourth Edition (DSM-IV-TR). 3. Mortality: Data on mortality were obtained from coroner's reports and hospital records for participants who died during the study period for medical (nonpsychiatric) reasons. 4. Laboratory Tests: Screening laboratory tests were carried out at baseline and annually thereafter. These tests included a complete blood count and differential, liver function tests, and serology for hepatitis C virus (HCV) and human immunodeficiency virus (HIV). The aspartate aminotransferase-to-platelet ratio index (APRI) was used as a surrogate measure for hepatic fibrosis. These methods provided a comprehensive set of data for analyzing the associations between substance use, psychosis, and mortality among the study participants. More detailed descriptions of the annual and monthly assessments, along with references, are stated to appear in open-source publications and associated supplements. Assessment of time-invariant risk factors for psychotic features: The image you've provided appears to be a section from an academic article discussing the assessment of time-invariant risk factors for psychotic features. It explains that time-invariant risk factors are those that occurred in the past and/or are not modifiable, such as a past diagnosis of a psychotic disorder, persistent sequelae from past traumatic brain injury (TBI), and exposure to early-life traumatic events (any, and homelessness by age 18). The assessment of these factors included clinical interviews, magnetic resonance imaging (MRI) findings, and the use of standardized measures like the Trauma History Questionnaire (THQ). The THQ is scored based on the number of types of traumatic events experienced, with a maximum of 23 different types, including physical, sexual, disaster-related, or crime-related events. Additionally, the number of types of traumatic events experienced prior to age 18 (THQ18) is also considered. This section highlights the importance of considering both modifiable and non-modifiable risk factors when assessing the potential for psychotic features in individuals, particularly in a population that has experienced homelessness or precarious housing. Understanding these risk factors can help in developing targeted interventions and support for those at risk of psychosis."

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Other Subject: How baseline assessments were conducted with participants
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