How are the mechanisms of action and modes of action


Essay Assignment

Imagine that you are an industrial hygienist or a safety officer, and you have been asked to create a safety data sheet (SDS) for the employees within the manufacturing facility where you work. However, in this assignment, you will not actually create the SDS. You will just be collecting and studying specific data about the toxicity of certain chemicals that could be used to create it. Assume that the following chemicals/compounds are released during the manufacturing process:

benzene,
vinyl chloride,
asbestos,
ammonia, and
hydrogen chloride.

Choose one of these chemicals, and review the toxicology data for it. Create at least a three-page essay which outlines the following information about the chemical:

1. How can the route of exposure affect the toxicity of the chosen chemical/compound?

2. How are the mechanisms of action and modes of action established surrounding how to deal with exposure to the chemical/compound?

3. What are the effects that the chemical/compound chosen can have on the human body from the initial exposure to elimination?

Your essay should also discuss how the Bradford Hill criteria for causation is used to determine the strength of the toxicology data you reviewed. The essay should be at least two pages in length (not counting the title and reference pages) and should utilize proper APA citations and references.

The websites below are good places to begin looking for information regarding your specific chemical/compound:

Agency for Toxic Substances & Disease Registry Occupational Safety and Health Administration.

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Chemistry: How are the mechanisms of action and modes of action
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