How are effects of x inactivation noticeable in heterozygote, Biology

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How are effects of x inactivation noticeable in heterozygote

Problem

a) How does X inactivation compensate for differences between males and females in the number of copies of genes on the X chromosome? How are the effects of X inactivation noticeable in heterozygotes?

b) What is genomic imprinting and how can abnormal imprinting cause disease?

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Biology: How are effects of x inactivation noticeable in heterozygote

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