Give standard process calculations for sterilization


Problem: In a continuous fluid sterilizing operation, you have included in your standard process calculations for sterilization that your holding tube holds the product at 118 oC with a residence time of 7 min. One morning, you discover from the product output that your fluid pump has unaccountably increased the flow rate by 30% and the only available way to correct in the short term and get usable product is by lifting the holding temperature. To what new temperature should you lift it? You check out the sensitivity of the spore destruction and find that it is 26% oC at these temperatures. The activation energy for this spore death is 298kJ /mol; the gas constant, is 8.314J/mol K; the temperature is 118 oC=391K

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