Discuss contribution of complement to inflammatory response


Problem

Read the article "The Role of Complement in Inflammatory Diseases From Behind the Scenes into the Spotlight" by Maciej M. Markiewski and John D. Lambris.

Answers to the questions should be based on the information in this article only. The assessment will assess how the information within the article has been analysed and how the information is used to answer the questions below.

I. Discuss the contribution of complement to the acute inflammatory response. Use the information in the article to support the discussion. The answer should include discussion of anaphylatoxins and opsonins and their role in inflammation. Do not describe the complement activation pathways.

II. Discuss the link between complement and disease. Use the information in the article to support the discussion which should include discussion of the link between complement, adaptive immunity and disease.

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