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Describe the mechanism of action of eicosanoids give

1. Present the comparison of neuromuscular blocking drugs and local anesthetics. What is a rationale to use them for pain control?

2. Present the rationale for clinical applications of COX inhibitors. What is a difference between COX-1 and COX-2 activity blocking drugs? How can they be used in clinical practice?

3. Describe the mechanism of action of eicosanoids. Give examples of eicosanoids used to treat bronchoconstriction and inflammatory cell infiltration of the bronchi.

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