Question: Describe the HIV screening and confirmation process i. HIV-1/2 antigen/antibody combination immunoassay 1. How long after exposure will this detect? • ELISA (enzyme-linked immunosorbent assay) o HIV-1/2 antigen/antibody combination immunoassay Detects HIV-1 and HIV-2 antibodies (IgG and IgM) New generation tests also detects antigens (p24) o >99% sensitivity, >99% specificity o False positives: rare o False negatives: may occur Most commonly occur if testing before production of antibodies and/or antigens Minimum time to produce antibodies: 3-4 weeks Newest tests can detect within 15-20 days of acquisition (due to antigen detection) 95% of individuals have antibodies in 6 months. Need Assignment Help?