Problem
i. Define innate immunity and how it works broadly (HINT: what is two major molecular components needed for innate immunity).
ii. There are Toll-like receptors that are found in the plasma membrane, while others are on the endosomal membrane. What is the advantage of having TLRs on PM and endosomes?
iii. On the other hand, NODs are cytosolic receptors. What is the point of having innate immune receptors in the cytosol? And why should NOD promote xenophagy (HINT explain what xenophagy is)?