Construct an Excel spreadsheet performing an ANOVA analysis for a randomized complete block design involving four samples hybridized simultaneously (using a four-channel technology) on six arrays. Use random numbers as experimental values. Then change the numbers corresponding to one mRNA sample such that the mean of that sample is lower. See how much the mean can go down without the F test showing a significant difference between the different samples. Settle on a data set such that the p-value is barely below 0.05.