Question 1 Which one of the following agents inhibits specifically leukotriene receptors
Ibuprofen (Advil)
Fexofenadine (Allegra)
Zafirlukast
Zileuton
Cromolyn
Question 2 Which one of the following agents would be the drug of choice to reduce the likelihood of platelet aggregation and thrombotic events in patients predisposed to myocardial infarctions?
Acetaminophen (Paracetamol)
Sulindac (Clinoril)
Phenylbutazone
Cimetidine (Tagamet)
Aspirin
Question 3 Which one of the following NSAID's has a sulfide metabolite with a half-life of up to 18 hours?
Indometahcin (Indocid)
Ibuprofen (Advil)
Sulindac (Clinoril)
Aspirin
Celecoxib (Celebrex)
Question 4 Low dose aspirin is indicated in patients with myocardial infarction. The other drug of choice to reduce recurrence of MI's would be??
Nifedipine
Propranolol
Lidocaine
Quinidine
Verapamil
Question 5 Which one of the following NSAID's has the highest specificity for the cyclooxygenase-2 enzyme?
Celecoxib (Celebrex)
Ibuprofen (Advil)
Aspirin
Indomethacin (Indocid)
Diclofenac (Voltaren)
Question 6 Which one of the following NSAID's is likely to cause Reye's syndrome in pediatric patients?
Aspirin
Ibuprofen (Advil)
Indomethacin (Indocid)
Diclofenac (Voltaren)
Celecoxib
Question 7 The hepatotoxicity caused by an overdose of acetaminophen is due to ?
Direct effects of acetaminophen on hepatic tissue
The effects of glutathione conjugation
The effects of glucoronidation
The effects of NAPQI
All of the above
Question 8 Which one of the following conditions is likely to exacerbate acetaminophen toxicity?
Acute alcohol
Grapefruit juice
Chronic alcohol
Corticosteroids
Aspirin
Question 9 Acetaminophen toxicity is treated with?
Deferoxamine
Dimercaprol
N-acetylcysteine
Propranolol
Amifostine
Question 10 Celecoxib is contraindicated in patients who have?
Gastrointestinal distress
Myocardial issues
Thyroid dysfunction
Migraine
Myaesthenia Gravis