Autosomal recessive genetic disorder
Mr. Smith's father and Mrs. Smith brother each have the same rare, autosomal recessive genetic disorder; Mr. and Mrs. Smith are both unaffected. What is the prior probability that both Mr. and Mrs. Smith are carriers of the affected allele?
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(1) In Drosophila, the gene for miniature wing "m" is recessive to wild type wing allele. A female heterozygous for both traits was mated to a vermilion-eyed, miniature-winged male
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