Problem: For asymptomatic patients not requiring treatment, the NCCN recommends serial monitoring with history, physical examination, and CBC with differential every 3-6 months. [1] CT scans are not required for routine monitoring outside of clinical trials. [1] Patients should be evaluated at each visit for the development of treatment indications, including progressive cytopenias, symptomatic or bulky disease, B symptoms, and threatened end-organ function rewrite. Need Assignment Help?