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anabolic reactions the intermediates of citric acid cycle are used as precursors in tlie biosynthesis of many compounds like
functions of citric acid cyclethe citric acid cycle is an amphibolic pathway ie it is involved in both anabolic and catabolic
explain citric acid cyclein the citric acid cycle the oxaloacetate is first condensed with acetyl coa and then regenerated as the
genetic defect in pyruvate dehydrogenasea defed in any of the protein subunits of pdh can result in decrease or complete loss of activity
oxidation of pyruvate to acetyl coathe oxidation of pyruvate to acetyl coa is the irreversible route from glycolysis to the citric
fluoride inhibitorfluoride inhibits enolase enzyme involved in the conversion of 2-phosphoglerate to phosphoenol
what is arsenite inhibitorarsenite inhibits synthesis of atp in the conversion of 13-bisphosphoglycerate to 3- phosphoglycerate by
what is iodoacetate inhibitoriodoacetate is the inhibitor of glyceraldehyde-3-phosphate
how to increase in the amount of glucokinase in liverconsumption of a meal rich in carbohydrate or administration of insulin initiate an
phosphofiuctokinase-i phosphofiuctokinase-i is activated by amp and inhibited by atp and citrate when atp is utilized in energy requiring
regulation of glycolysisthere are three markedly exergonic reactions in the glycolytic pathway which are considered physiologically
oxidative decarboxylation of pyruvateoxidative decarboxylation ofpyruvate this is an important step in tissues with high oxidative capacity such as
what is gluconeogenesisthere is accumulation of lactate which is released into the blood and taken up by the liver where it is converted
formation of lactate and its consumptionformation of lactate and its consumption if anaerobic conctitions prevail the reoxidation
pyruvatepyruvate has three different fates under aerobic conditions pyruvate enters mitochondriaand is converted to acetyl coa the acetyl coa
shift of the phosphate group from carbon 3 to carbon 2shift of thephosphate group form carbon 3 to carbon 2 this reversible reaction is catalyzed
oxidation of glyceraldehyde-3-phosphateoxidation of glyceraldehyde-3-phosphate the conversion of glceraldehyde- 3-phosphate to
isomerization of dihydroxyacetone phosphateisomerization of dihydroxyacetone phosphate triosephosphate isomerase interconverts
cleavage of fructose-16-bisphosphate aldolase cleaves fructose-1 6-bisphosphate to dihydroxyacetone phosphate and glyceraldehyde-3-phosphate in
phosphorylation of fructose-6-phosphatephosphorylation of fructose-6-phosphate this is an irreversible reaction catalyzed
isonzerization of glucose-6-phosphateisonzerization of glucose-6-phosphate this step is catalyzed by phosphoglucoisomerase
phosphorylation of glucoseglucose is converted to glucose-6-phosphate since phosphorylated intermediates do not readily penetrate cell
carbohydrate metabolismcarbohydrates are broken down into monosaccharides which are absorbed into the blood stream in
explain endonucleases endonucleases are nucleases present in the pancreatic juice like rnaase anddnaase these hydrolyze internal
the various organs involved in the digestion process arealimentary tract which includes mouth pharynx esophagus stomach small intestine