Mechanism of Pathogenesis:
The foreign serum and antibodies against it form immune complexes. Such immune complexes get deposited on the endothelial lining of blood vessels in different portions of the body causing inflammatory reaction. With more quantity of antibody production such immune complexes are phagocytosed. This reaction turns into self restricted.Glomerulonephritis:
Acute post streptococcal glomerulonephritis is a familiar immune complex disease. Its onset takes place quite a few weeks after a group. A beta hemolytic streptococcal infection.
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