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  Diseases caused by Mycoplasmas

Diseases caused by Mycoplasmas:

In Humans a few are normal inhabitants of genitourinary tract, mainly females. In pregnant women it is related with chorioamnionitis, post partum fever and low birth weight of new borns. U.urealyticum needs 10 percent urea for growth. It causes non gonococcal urethritis and might cause male infertility. M. pneumonia causes pneumonia.

In Animals mycoplasma causes pleura-pneumonia that is a contagious disease of the cattle, having occasional deaths.

Human infections:

There are over 150 species in the group of cell wall free bacteria termed as Mollicutes. At least 15 of such species are thought to be of human origin. In humans 4 species are of main significance. Mycoplasma pneumoniae causes pneumonia and combined infections. Mycoplasma hominis generates post partum fever, and uterine tube infections. Ureaplama urealyticum is related with non gonoccal urethritis, lung diseases and in premature baby of low birth weight. Mycoplama genitalium is associated to M.pneumoniae, and causes pneumonia as well urethral and other infections.

Mycoplasma pneumoniae:

The morphology emerges different according to techniques of examination. Growth in fluid media gives mount to many various forms involving rings, spiral bodies, bacillary, filaments and granules. Growth on solid media comprises of plastic protoplasmic masses of indefinite shape which are easily distorted. M. pneumoniae causes atypical pneumonias.

Pathogenesis:

From the respiratory secretions via inhalation organisms enter the respiratory tract. They join to the receptor on the respiratory epithelial cells, multiply and cause disease.

 

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