Attributes of Staphylococcus aureus:
S.aureus generates various substances to evade or overcome host defenses. Such substances are enzymes and toxins. They are:
(1) Catalase: It is an enzyme that splits hydrogen peroxide to water and oxygen. (2) Coagulase: This is an enzyme like protein. It clots plasma, fibrin is deposited above the organism and therefore it escapes from the attack by phagocytic cells.
(3) Hyaluronidase: It is also termed as spreading factor. With its help staphylococci can spread via tissues.
(4) Staphylokinase: This lyses the fibrin clot.
(5) Proteases: These are enzymes which split proteins
(6) Lipases: These are enzymes which degrade lipids.
(7) Betalactamase: This enzyme is generated by some strains of staphylococci that splits penicillin molecule
(9) Leukocidins: These toxins destroy white blood cells.
(10) Exfoliative toxin:It causes the peeling off of squamous epithelial cells of skin. Such toxin is responsible for a condition termed as scaled skin syndrome
(11) Toxic shock syndrome toxin (TSS toxin): It is related with fever, shock and multisystem involvement.
(12) Enterotoxins: These are accountable for causing food poisoning.
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