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  Nonoxidative phase

Nonoxidative phase:

In Nonoxidative phase, several intermediates like 3C, 4C, 5C and 7-carbon phosphorylated sugars are generated. They are phosphoglyceraldehyde or 3C, xylulose phosphate or 5C, erythrose phosphate or 4C, and sedoheptulose phosphate or 7C.

To shorten, 6 molecules of glucophosphate come in this pathway. Later than oxidation, six molecules of CO2 are gets released as displayed in the step 4 and 12 molecules of NADPH2 are generated as displayed in the steps 2 and 4. Other words, later than oxidation one molecule of glucose generates 6 molecules of CO2 and twelve molecules of NADPH2. Out of 6 glucose molecules one is totally oxidized and another five molecules are included in the creation of 3C, 4C, 5C, and 7- carbon sugar intermediates. From these intermediates, 5 molecules of glucose-6-phosphate are reproduced.

Significance of pentose phosphate pathway

1. It gives alternative route for carbohydrate breakdown.

2. It produces NADPH2 molecules that are employed like reductants in biosynthetic processes. Generation of NADPH2 is not related to ATP generation in pentose phosphate pathway.

3. It gives ribose sugar for the synthesis of nucleic acids.

4. It gives erythrose phosphate needed for the synthesis of aromatic compounds.

5. It plays a vital role in fixation of CO2 in photosynthesis by Ru5P.

 

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