Biosynthesis of cholesterol:
Significant intermediates of cholesterol Biosynthesis and enzymes included.
1. Formation of acetyl CoA:
A molecule of acetic acid combines along with coenzyme A (CoA) to generate Acetyl CoA in the existence of an enzyme Acetyl CoA synthetase.
2. Formation of acetoacetyl CoA:
Two molecules of acetyl-CoA condense to create an acetoacetyl- CoA molecule, catalyzed via the enzyme “thiolase”.
3. Formation of HMG CoA:
The acetoacetyl-CoA further goes through condensation with one more molecule of acetyl-CoA to create HMG-CoA (3-Hydroxy 3-Methyl Glutaryl-CoA). The enzyme that mediates this reaction is known as HMG- CoA synthetase.
4. Formation of mevalonate:The HMG-CoA is gets reduced to create mevalonate by NADPH + H+ dependent reductase (HMG-CoA reductase). In the pathway of cholesterol biosynthesis this is the rate limiting enzyme.
5. So mevalonate formed is then transformed to squalene by various steps.
6. Squalene, along with the formation of several intermediates at last gives rise to the end product cholesterol.
Diagram: Biosynthesis of Cholesterol
Latest technology based Biology Online Tutoring Assistance
Tutors, at the www.tutorsglobe.com, take pledge to provide full satisfaction and assurance in Biosynthesis of cholesterol homework help via online tutoring. Students are getting 100% satisfaction by online tutors across the globe. Here you can get homework help for Biosynthesis of cholesterol, project ideas and tutorials. We provide email based Biosynthesis of cholesterol homework help. You can join us to ask queries 24x7 with live, experienced and qualified online tutors specialized in Biosynthesis of cholesterol. Through Online Tutoring, you would be able to complete your homework or assignments at your home. Tutors at the TutorsGlobe are committed to provide the best quality online tutoring assistance for Biology homework help and assignment help services. They use their experience, as they have solved thousands of the Biology assignments, which may help you to solve your complex issues of Biosynthesis of cholesterol. TutorsGlobe assure for the best quality compliance to your homework. Compromise with quality is not in our dictionary. If we feel that we are not able to provide the homework help as per the deadline or given instruction by the student, we refund the money of the student without any delay.
tutorsglobe.com locks assignment help-homework help by online operating system tutors
Theory and lecture notes of Money, Prices and Inflation all along with the key concepts of money, prices, and inflation, The Usefulness of Money, Units of Account, Coincidence of Wants. Tutorsglobe offers homework help, assignment help and tutor’s assistance on money, prices and inflation.
Redox Titrations tutorial all along with the key concepts of Theory of redox titrations, Preparation of KMnO4 solution, Computations by using the half-reaction method, Determination of the Mass of Iron in a Ferrous Solution
criteria for spontaneity tutorial all along with the key concepts of ternal energy change as a criterion for spontaneity, enthalpy change as a criterion for spontaneity, helmholtz free energy change, gibbs free energy change as a criterion for spontaneity, nernst heat theorem
the fourth generation computers uses large scale integrated circuits (lsic) developed a single silicon chip called microprocessors.
Reflex and Complex Behavior tutorial all along with the key concepts of Definition of Reflex, Complex Behavior Patterns, Animal and motivation, Bottom-up approaches vs. black-box approaches, Nervous systems of animals, Ethology, Kineses and taxes
Regulatory Systems and Mechanisms in Animals tutorial all along with the key concepts of Homeostasis process, Homeostatic process, Regulation of Body Temperature, Regulation of Muscular Movement, Regulation of Hormone Production.
The requirement for uniform costing arises since the cost structures and procedures, practices and principles of costing different from firm to firm, business to business and industry to industry.
tutorsglobe.com impact of air pollution on human health assignment help-homework help by online air pollution tutors
Isolation-Structure Determination of Natural Products tutorial all along with the key concepts of General Methods of Extraction, Aqueous extraction of compounds, Fractionation, Fractionation by chromatography, Adsorption chromatography
theory and lecture notes on the concept of fundamental electric circuit laws and ohms law all along with the key concepts of ohm’s law, kirchhoffs circuit laws, kirchhoffs current law and kirchhoffs voltage law. tutorsglobe offers homework help, assignment help and tutor’s assistance on the concept of fundamental electric circuit laws and ohms law.
tutorsglobe.com biosynthesis of phospholipids assignment help-homework help by online phospholipids tutors
tutorsglobe.com earnings per share assignment help-homework help by online governing a company tutors
gramophone is a type of record player. the sound that is stored in the place is converts in to an electrical note through a tone arm.
tutorsglobe.com reserve money assignment help-homework help by online money tutors
1950171
Questions Asked
3689
Tutors
1454631
Questions Answered
Start Excelling in your courses, Ask an Expert and get answers for your homework and assignments!!