The lipid molecules form a constant bilayer. The protein molecules are arranged as extrinsic proteins on the surface of lipid and as intrinsic proteins which penetrate the lipid bilayer either completely or partially. The lipid bilayer is formed of a double layer of phospholipid molecules. They are an amphipathic molecule that is; they have a hydrophobic and hydrophilic part. The arrangement of phospholipids forms a water resistant blockade. So that merely lipid soluble substances can pass through readily however not water soluble substances. The phospholipid bilayer builds the basic structure of all bio-membranes that also include proteins, glycoproteins, cholesterol and other glycolipids and steroids. The existence of particular sets of membrane proteins allows each kind of membrane to bring out distinctive functions.

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