Dominant Epistasis-12:3:1

This kind of interaction was mentioned by Sinnott in summer squash (that is, Cucurbita pepo).

In Cucurbita pepo there are three general fruit colors yellow, white, and green. White color is generated due to the existence of dominant gene W. In the deficiency of W, the dominant gene Y generates yellow fruit color and the double recessive is green. The effect of dominant gene `Y' is masked by the dominant gene `W' that is the epistatic gene therefore this is termed as dominant epistasis.

Whenever pure breeding white fruited diversity is crossed with the double recessive green variety, the F₁ hybrids are all white. Whenever the hybrids are white, selfed, yellow and green fruited plants occur correspondingly in the ratio of 12:3:1.

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