Enzymatic reaction-Effect of a substance

Question

In support of enzymatic reaction write down the effect of a substance with same spatial conformation as enzymatic substrate? How is this kind of substance recognized?

Answer 1

Substances which ‘simulate’ substrates can bind to activation center of enzymes therefore blocking true substrates to bind to these enzymes and paralyzing enzymatic reaction. Such ‘fake substrates’ are named as enzyme inhibitors. The binding of enzyme inhibitors to the enzymes can be irreversible or reversible. Many of medical drugs, for instance, some antibiotics, antineoplastics, antivirals, antihypertensives as well as even sildenafil (or trade name Viagra), are enzyme inhibitors which block the enzyme activity.